Women's Health 2040

Discipline attraction and preclinical models

A Nordic funder-level preclinical mandate paired with one shared facility under the SIRF framework.

Timeline 2026–2028High impactMoney

Women's health draws from a narrow pool of already-committed researchers. Targeted attraction calls increase field diversity by 25–40 % within two funding cycles — pulling cardiologists, neurologists, and AI scientists into women's health for the first time.

Transformation

From

Cardiologists, AI and data scientists, epidemiologists, and health economists are not pulled into women's health at scale; no Nordic-level mandate exists for sex-inclusive preclinical infrastructure (animal models, female cell lines, tissue biobanks staged by reproductive phase), and preclinical-to-clinical translation continues to fail women

To

A Nordic funder-level preclinical mandate on the UK MRC (Sep 2022) and NIH SABV (2016) model, paired with one shared Nordic facility under the SIRF framework — closing the architectural gap that has narrowed the evidence base for three decades

Description

Two grouped requirements sit under this need. The first is funding instruments that pull cardiologists, AI and data scientists, epidemiologists, and health economists into women’s health. The second is funding for sex-inclusive preclinical infrastructure, meaning animal models, female cell lines, and tissue biobanks staged by reproductive phase. Most women’s health questions are biological-system questions before they are reproductive-system questions. Without cardiologists and female cell lines, the evidence base stays narrow, and preclinical-to-clinical translation continues to fail women at the rate it has done for the past three decades.

A Nordic funder-level preclinical mandate on the model of the one adopted by UK MRC in September 2022, and the NIH SABV policy in force since 2016, paired with one shared Nordic facility operating under the SIRF framework, would close the architectural gap. The question of discipline attraction is already being addressed structurally through centre design, and does not require a separate instrument. The five national research councils are positioned to lead on the funder-mandate side, and the existing centres on the facility side.

Evidence anchors

UK MRC sex-inclusive preclinical mandate. September 2022 funder-level requirement for sex-inclusive preclinical research — the closest model for Nordic adoption.
NIH SABV (Sex As a Biological Variable) policy. In force since 2016 — a decade of operational experience embedding sex as a biological variable in funded research.
SIRF (Shared Infrastructure for Research Facilities). Existing framework under which Nordic shared facilities can operate — receives the women's-health preclinical infrastructure layer without new architecture.

At a glance

Natural lead
Five national research councils (funder-mandate); existing centres of excellence (facility)
Indicative investment
€2–4M across national councils

Entry points

  • NordicCoordinate call design across councils
  • NationalLaunch calls through national research councils
  • RegionalUniversity departments promote calls to adjacent researchers

Indicators

Output

  • Calls launched across 3+ countries
  • 50+ first-time WH grants awarded
  • Sustained cross-disciplinary pipeline

Handoff

  • New researchers connected to WH mentors
  • Cross-disciplinary publications emerging
  • Adjacent-field researchers become WH leaders

Outcome

  • Increased diversity of WH research applications
  • New female preclinical models validated

Building on

Nordic foundations

SIRF frameworkExisting Nordic centres of excellenceFive national research councils

International inspirations

UK MRC preclinical mandateNIH SABV policy

Connected needs

Cite this need

Cite this need

Persson, J. (2026). R-M-1 Discipline attraction and preclinical models. In The Nordic Implementation Playbook for Women's Health 2040. CIFS. https://womenshealth2040.org/playbook#r-m-1

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